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Tidal volume
Tidal volume is the lung volume representing the normal volume of air displaced between normal inhalation and exhalation when extra effort is not applied. In a healthy, young human adult, tidal volume is approximately 500 mL per inspiration or 7 mL/kg of body mass.〔Beardsell, I et al: ''MCEM Part A:MCQs'', page 33, Royal Society of Medicine Press, 2009〕
==Mechanical ventilation==
Tidal volume plays a significant role during mechanical ventilation to ensure adequate ventilation without causing trauma to the lungs. Tidal volume is measured in milliliters and ventilation volumes are estimated based on a patient's ideal body mass. Measurement of tidal volume can be affected (usually overestimated) by leaks in the breathing circuit or the introduction of additional gas, for example during the introduction of nebulized drugs.
Ventilator-induced lung injury such as ALI/ARDS can be caused by ventilation with very large tidal volumes in normal lungs, as well as ventilation with moderate or small volumes in previously injured lungs, and research shows that the incidence of ALI increases with higher tidal volume settings in nonneurologically-impaired patients.
Initial settings of mechanical ventilation:
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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